Description
Core Product Summary
The Agilent G1946-80060 is a high-energy dynode power supply assembly designed for Agilent LC/MS mass spectrometry equipment. Its function is to provide the high-voltage supply required by the HED ion detection stage while supporting fast polarity switching.
The assembly is identified for Agilent 6100 Series single-quadrupole and 6400 Series triple-quadrupole LC/MS instruments. It is also listed as the HED power supply for specific G1946B/D and G1956B instrument configurations. When selecting this component for equipment maintenance or replacement, the instrument model, hardware configuration, and existing power-supply part number should be checked together.
Key Technical Specifications
| Parameter | Specification |
|---|---|
| Manufacturer | Agilent Technologies |
| Part Number | G1946-80060 |
| Product Type | High-Energy Dynode (HED) Power Supply |
| Component Category | High-Voltage Power Supply Assembly |
| Instrument Technology | LC/MS |
| Switching Function | Fast polarity switching |
| Supported Instrument Families | 6100 Series Single Quadrupole LC/MS; 6400 Series Triple Quadrupole LC/MS |
| Associated Instrument Configurations | G1946B/D and G1956B |
| Primary Function | HED high-voltage power supply |
| UNSPSC Code | 41115700 |
Engineering Selection Highlights
- HED power-supply identification: G1946-80060 is specifically identified as a high-energy dynode power supply. This distinguishes it from the instrument’s other high-voltage and general power-supply assemblies.
- Fast polarity switching: Its fast-switching design supports LC/MS configurations requiring rapid changes in ion polarity.
- 6100 Series integration: Agilent lists the component for 61XX single-quadrupole LC/MS instruments.
- 6400 Series integration: The part is also designated for 64XX triple-quadrupole LC/MS platforms.
- Instrument-specific replacement: Confirm the installed HED assembly part number and instrument configuration before ordering.
- Electrical subsystem maintenance: Its role within the mass spectrometer’s high-voltage subsystem makes correct part identification important during servicing.

G1946-80060

G1946-80060
System Compatibility & Integration Requirements
| Item | Compatibility / Requirement | Practical Consideration |
|---|---|---|
| Instrument technology | Agilent LC/MS | Intended for liquid chromatography/mass spectrometry equipment. |
| Single-quadrupole platform | Agilent 6100 Series (61XX) | Check the instrument’s installed configuration. |
| Triple-quadrupole platform | Agilent 6400 Series (64XX) | Confirm the exact instrument model and service configuration. |
| Power-supply subsystem | High-energy dynode (HED) | Must match the installed HED assembly specification. |
| Switching function | Fast polarity switching | Relevant to instruments configured for fast polarity-switching operation. |
Replacement identification note
G1946-80060 should not be selected solely because another Agilent LC/MS component has a similar part-number prefix. HED power supplies, detector assemblies, and other high-voltage modules perform different functions. Compare the complete part number against the instrument’s parts list before replacement.
Detailed Product Overview
High-Energy Dynode Power Supply Function
The Agilent G1946-80060 is an electrical assembly associated with the high-energy dynode section of an LC/MS instrument.
In mass spectrometry, ions are separated according to their mass-to-charge ratios before reaching the detection stage. The detector’s electrical supply is an important part of the instrument’s signal-detection architecture. The HED power supply provides the required high-voltage power for this subsystem.
Because the G1946-80060 is identified specifically as an HED power supply, it should be distinguished from other power assemblies used for RF generation, ion-source operation, and general instrument power distribution.
Fast Polarity Switching
Agilent identifies fast polarity switching as a defining characteristic of this assembly.
LC/MS methods may require measurements in both positive-ion and negative-ion modes. Fast polarity switching supports workflows that change between these modes during analytical acquisition.
The power-supply assembly must therefore be considered within the complete instrument configuration. Its presence alone does not establish that every LC/MS model or analytical method supports the same switching performance.
Integration with Agilent LC/MS Platforms
The G1946-80060 is listed for two major Agilent instrument categories:
- 6100 Series single-quadrupole LC/MS.
- 6400 Series triple-quadrupole LC/MS.
These instrument families use different mass-analyzer architectures, but both require dedicated electrical subsystems to support their operating functions.
For maintenance engineers, the distinction between the HED supply and other internal power assemblies is particularly important. Selecting a component based only on its general description or physical appearance can result in an incorrect replacement.
Maintenance and Replacement Considerations
When identifying the G1946-80060 for maintenance, several points should be considered:
- Record the complete instrument model and serial number.
- Check the existing HED power-supply part number.
- Confirm that the replacement corresponds to the instrument’s hardware configuration.
- Inspect associated electrical connections and high-voltage interfaces during servicing.
- Follow the instrument-specific service procedure when removing or installing the assembly.
- Perform the required instrument checks after replacement.
High-voltage assemblies should only be serviced by appropriately qualified personnel following the instrument manufacturer’s safety procedures.
Applications & System Role
The G1946-80060 occupies a specialized position in the electrical architecture of an Agilent LC/MS instrument.
Its primary role is to provide the high-energy dynode power required by the HED subsystem. The fast-switching capability is relevant to mass spectrometry workflows that alternate between positive-ion and negative-ion acquisition modes.
Typical functional application areas include:
- Single-quadrupole mass spectrometry: HED power-supply support in Agilent 6100 Series instruments.
- Triple-quadrupole mass spectrometry: High-energy dynode power supply integration in Agilent 6400 Series equipment.
- Polarity-switching workflows: Supporting the electrical requirements of fast polarity-switching operation.
- LC/MS instrument servicing: Replacement of the corresponding HED power-supply assembly during equipment maintenance.
- Mass spectrometer electrical maintenance: Troubleshooting and maintenance involving the high-voltage power subsystem.
Frequently Asked Questions
Q1: What is the Agilent G1946-80060?
The Agilent G1946-80060 is a fast-switching high-energy dynode power supply used in Agilent LC/MS mass spectrometry systems.
Q2: Which instruments use the G1946-80060?
It is listed for Agilent 6100 Series single-quadrupole and 6400 Series triple-quadrupole LC/MS instruments.
Q3: What does HED mean in G1946-80060?
HED stands for High-Energy Dynode. It identifies the power-supply function associated with the instrument’s high-energy dynode subsystem.
Q4: Does the G1946-80060 support fast polarity switching?
Yes. Fast polarity switching is part of the product’s specified function.
Q5: Is the G1946-80060 a complete mass spectrometer?
No. It is an internal electrical power-supply assembly intended for integration into compatible LC/MS equipment.
Q6: What should be checked before purchasing this part?
Check the instrument series, complete model number, serial number, existing HED power-supply part number, and hardware configuration.
Q7: Can the G1946-80060 replace other Agilent high-voltage power supplies?
It should not be treated as a universal replacement. Different high-voltage assemblies serve different functions, and replacement suitability depends on the instrument’s documented configuration.




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